Sarcopenic Obesity-A Minireview-Does it Lead to a Greater Incident of Type 2 Diabetes, Metabolic Syndrome or Mortality than When Sarcopenia or Obesity Exist Separately

Sarcopenia is an age related process that is characterized by a progressive loss of skeletal muscLe and strength. This condition is of major health concern in older adults since it has been associated with metabolic impairments, cardiovascular disease(CVD) risk factor along with physical and functional disability and increases the risk of early mortality. Sarcopenia often coexists with obesity leading to a specific condition called ‘’sarcopenic obesity’’(SO). Current evidences implicate that SO maybe associated with a large number of metabolic disorders and an increased risk of mortality than obesity or sarcopenia alone. However few studies have been conducted in this field and with contradictory results. Cross sectional studies in SO subjects have documented greater prevalence of cardiovascular risk factors and metabolic syndrome in these subjects. A strong association of inflammatory markers compared with sarcopenia only subjects have been found. While some longitudinal studies have shown that SO Does not apparently confer any greater mortality risk than sarcopenia alone. Thus we conducted a systematic review to analyze the coexistence of the 2 and relative increased incidence of Type2 diabetes mellitus (T2DM) in SO and its long term outcomes in studies that had used biomedical impedance, dual XRay absorptiometry with BMI, WC etc along with free fat mass, free fat muscle mass etc.

Keywords: SO,T2DM,; Sarcopenia; Mortality, BIA, BMI, DXA.